There are few identified risk factors for prostate cancer. The most prominent risk factor is age. The average age at the time of diagnosis is 72 years of age, and greater than 80% of tumors occur in men older than 65 (50). Among ethnic groups that have been studied in the United States, African Americans have the highest risk of developing prostate cancer. Although there are limited data on prostate cancer risk in American Indians, the available data suggest that their risk is comparable to that of Caucasians (50). Family history is a risk factor for prostate cancer, with first-degree relatives having the greatest risk.
The only modifiable risk factor is a diet rich in monosaturated fats, which is associated with a slightly increased risk in epidemiologic studies. Because most risk factors for this disease are not modifiable, there are no currently accepted prevention strategies. Therefore efforts are directed at screening strategies to reduce the burden of disease.